Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.44 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL4855093 | 0.97 | — | — | |
| SCHEMBL2167668 | 0.97 | — | — | |
| SCHEMBL4850698 | 0.90 | CASP1 (0.30) | CASP1 | |
| SCHEMBL31560796 | 0.90 | CASP1 (0.30) | CASP1 | |
| SCHEMBL4851288 | 0.90 | CASP1 (0.30) | CASP1 | |
| SCHEMBL31693522 | 0.83 | — | — | |
| Tribromoacetic Acid SCHEMBL2079154 | 0.81 | CA4 (0.39) | CA4FAHD1MEN1LDHABLM | |
| SCHEMBL28610481 | 0.80 | CA4 (0.35) | CA4FAHD1MEN1LDHABLM | |
| SCHEMBL4856888 | 0.75 | CASP1 (0.32) | CA4FAHD1CASP1CA1 | |
| Potassium Ion SCHEMBL4856941 | 0.75 | CA4 (0.32) | CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999108-A | Preparation method of difluorobromoacetate | 南通宝凯药业有限公司 | 2022-02-01 | — | — | CN | disclosed |