Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.48 |
| ▸ | CCND1 | P24385 | 2/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199808 | 0.82 | GAA (0.50) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL28732547 | 0.81 | LMNA (0.49) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL28732545 | 0.81 | MAOA (0.44) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL28732552 | 0.77 | ACP1 (0.43) | BACE1DCTPP1ABCG2ENPP1MAPT | |
| SCHEMBL30753422 | 0.76 | PIK3CA (0.49) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30659940 | 0.75 | GPR3 (0.66) | BACE1TRIM58DHFRMAPTALDH1A1 | |
| SCHEMBL8390259 | 0.73 | ABCG2 (0.54) | DCTPP1ABCG2 | |
| SCHEMBL1614546 | 0.72 | ALDH1A1 (0.50) | DHFRMAPTALDH1A1GAAKDM4E | |
| SCHEMBL14479463 | 0.72 | ALDH1A1 (0.50) | DHFRMAPTALDH1A1GAAKDM4E | |
| SCHEMBL15203018 | 0.72 | KIF11 (0.48) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114182273-A | Synthesis method of trifluoromethyl phenanthridine compound | 温州大学 | 2022-03-15 | — | — | CN | disclosed |