Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.88 |
| ▸ | PLG | P00747 | 1/20 | 0.81 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.78 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.75 |
| ▸ | TUBB | P07437 | 2/20 | 0.75 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.75 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.75 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.75 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.75 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.75 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.75 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.75 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.75 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.75 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131217 | 1.00 | CYP3A4 (0.88) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| Kumatakenin SCHEMBL29681818 | 0.95 | KDM4E (0.83) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| Kumatakenin SCHEMBL3351483 | 0.95 | KDM4E (0.83) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| Ermanin SCHEMBL2875089 | 0.94 | CYP3A4 (1.00) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| SCHEMBL11096763 | 0.91 | ABCG2 (0.77) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| SCHEMBL18130384 | 0.91 | ABCB1 (0.83) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| SCHEMBL828941 | 0.90 | PLG (1.00) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| SCHEMBL20100899 | 0.90 | CYP3A4 (0.80) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| SCHEMBL29825010 | 0.90 | PLG (1.00) | CYP3A4CYP2D6PLGNOX4ABCG2 | |
| SCHEMBL748643 | 0.88 | MAOA (0.90) | CYP3A4CYP2D6PLGNOX4ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106455665-B | Black ginger oil extract and preparation method thereof | 三得利控股株式会社 | 2020-06-30 | — | — | CN | claimed |
| US-20170071902-A1 | NOX INHIBITOR AND NFkB INHIBITOR CONTAINING METHOXYFLAVONE | SUNTORY HOLDINGS LIMITED (JP) | 2017-03-16 | — | — | US | claimed |
| US-20170065509-A1 | FAT OR OIL EXTRACT OF BLACK GINGER AND METHOD FOR PRODUCING SAME | SUNTORY HOLDINGS LIMITED (JP) | 2017-03-09 | — | — | US | claimed |
| CN-106455665-A | Fat or oil extract of black ginger and method for producing same | 三得利控股株式会社 | 2017-02-22 | — | — | CN | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| WO-1990006104-A1 | USE OF KAEMPFEROL AND CERTAIN DERIVATIVES THEREOF FOR THE PREPARATION OF A COSMETIC OR PHARMACEUTICAL COMPOSITION | LVMH RECHERCHE (FR) | 1990-06-14 | — | — | WO | claimed |
| US-4352792-A | 3-Alkoxyflavone antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 1982-10-05 | — | — | US | claimed |
| EP-0019081-A1 | Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-11-26 | — | — | EP | claimed |
| JP-2024028657-A | INTESTINAL TRACT BARRIER IMPROVER | 株式会社 資生堂 | 2024-03-04 | — | — | JP | disclosed |
| EP-3917554-B1 | METHOD FOR OBTAINING AN EXTRACT OF PATCHOULI LEAVES AND COSMETIC USES THEREOF | ISP INVESTMENTS LLC (US) | 2023-07-19 | — | — | EP | disclosed |
| CN-114891131-B | Extraction and purification process of vermicelli sedge polysaccharide | 贵州中医药大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115475157-A | Intestinal barrier improving agent | 株式会社资生堂 | 2022-12-16 | — | — | CN | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
| WO-1990006104-A1 | USE OF KAEMPFEROL AND CERTAIN DERIVATIVES THEREOF FOR THE PREPARATION OF A COSMETIC OR PHARMACEUTICAL COMPOSITION | LVMH RECHERCHE (FR) | 1990-06-14 | — | — | WO | disclosed |
| EP-0019081-B1 | FLAVONE DERIVATIVES, THEIR PREPARATION, THESE NOVEL AND KNOWN FLAVONES AS ANTIVIRAL AGENTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |
| US-4352792-A | 3-Alkoxyflavone antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0019081-A1 | Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065509-A1 | FAT OR OIL EXTRACT OF BLACK GINGER AND METHOD FOR PRODUCING SAME | FABP4, PLIN5, FABP6 | CYP3A4 184/4885CYP2D6 1611/4885PLG 3618/4885 |
| US-20170071902-A1 | NOX INHIBITOR AND NFkB INHIBITOR CONTAINING METHOXYFLAVONE | NOX1, NFKBIA, NOX5 | CYP3A4 1665/4885CYP2D6 2065/4885PLG 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.