Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876198 | 1.00 | ANPEP (0.42) | ANPEPMEP1BCTSK | |
| SCHEMBL405951 | 0.85 | MEP1B (0.43) | ANPEPMEP1B | |
| SCHEMBL12056257 | 0.85 | CTSS (0.41) | ANPEPCTSK | |
| SCHEMBL2875949 | 0.81 | ANPEP (0.45) | ANPEPMEP1BCTSK | |
| SCHEMBL4232154 | 0.81 | ANPEP (0.45) | ANPEPMEP1BCTSK | |
| SCHEMBL4232159 | 0.81 | ANPEP (0.45) | ANPEPMEP1BCTSK | |
| SCHEMBL2873414 | 0.81 | CTSB (0.43) | — | |
| SCHEMBL4525648 | 0.81 | CTSB (0.43) | — | |
| SCHEMBL4534760 | 0.80 | FFAR1 (0.45) | MEP1B | |
| SCHEMBL403767 | 0.78 | MMP2 (0.41) | ANPEPMEP1BCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | ANPEP 744/4885MEP1B 1047/4885CTSK 430/4885 |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | ANPEP 744/4885MEP1B 1047/4885CTSK 430/4885 |
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | ANPEP 744/4885MEP1B 1047/4885CTSK 430/4885 |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | ANPEP 744/4885MEP1B 1047/4885CTSK 430/4885 |
| US-20100324025-A1 | Antibacterial Agents | MRPL21, SI, PGLS | ANPEP 744/4885MEP1B 1047/4885CTSK 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.