Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448975 | 0.88 | PSIP1 (0.52) | PSIP1ALDH1A1HTTHSD11B1MMP1 | |
| SCHEMBL16485594 | 0.86 | PSIP1 (0.46) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL28763540 | 0.84 | PSIP1 (0.52) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL20996662 | 0.84 | MMP13 (0.65) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL28973817 | 0.84 | PSIP1 (0.52) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL28973785 | 0.84 | PSIP1 (0.52) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL2443006 | 0.82 | PSIP1 (0.55) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL6825821 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MMP1MMP13MAPTSMN1; SMN2 | |
| SCHEMBL7000851 | 0.81 | PSIP1 (0.48) | PSIP1ALDH1A1TP53HTTHSD17B10 | |
| SCHEMBL26361877 | 0.81 | PSIP1 (0.53) | PSIP1ALDH1A1TP53HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| US-20210290591-A1 | IMMUNOMODULATING UREA AZALIDES | ZOETIS SERVICES LLC | 2021-09-23 | — | — | US | disclosed |
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-15 | — | — | US | disclosed |
| EP-2776040-B1 | 4-PREGENEN-11SS-17-21-TRIOL-3,20-DIONE DERIVATIVES FOR THE TREATMENT OF OCULAR CONDITIONS | ALLERGAN INC (US) | 2020-04-22 | — | — | EP | disclosed |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-05-16 | — | — | US | disclosed |
| US-20180036233-A1 | SELF-EMULSIFYING DRUG DELIVERY (SEDDS) FOR OPHTHALMIC DRUG DELIVERY | ALLERGAN, INC. | 2018-02-08 | — | — | US | disclosed |
| US-20180036233-A1 | SELF-EMULSIFYING DRUG DELIVERY (SEDDS) FOR OPHTHALMIC DRUG DELIVERY | ALLERGAN, INC. | 2018-02-08 | — | — | US | disclosed |
| WO-2017143059-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-24 | — | — | WO | disclosed |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
| US-20040122218-A1 | Pyrrolopyridine potassium channel openers | ABBOTT LABORATORIES | 2004-06-24 | — | — | US | disclosed |
| US-6645968-B2 | E.g., N-(1-((anilinocarbonyl)amino)-2,2,2-trichloroethyl)-4-methyl-benzamide; antiepileptic, -ischemic and cardiotonic agents; sexual, eating and urogenital disorders; asthma; migraines; | ABBOTT LABORATORIES | 2003-11-11 | — | — | US | disclosed |
| WO-2003089404-A1 | NAPHTHALENE AMIDES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2003-10-30 | — | — | WO | disclosed |
| US-20030199578-A1 | Naphthalene amides as potassium channel openers | ABBOTT LABORATORIES | 2003-10-23 | — | — | US | disclosed |
| US-6495576-B2 | N-(1-((3,4-DIOXO-2-(3-PYRIDINYLAMINO)-1-CYCLOBUTEN-1-YL)AMINO) -2,2-DIMETHYLPROPYL)-4-METHYLBENZAMIDE FOR EXAMPLE; TREATING BLADDER OVERACTIVITY, BENIGN PROSTATIC HYPERPLASIA, PREMATURE LABOR, AND SEXUAL DISORDERS | ABBOTT LABORATORIES | 2002-12-17 | — | — | US | disclosed |
| US-20020165264-A1 | Aminal diones as potassium channel openers | ABBOTT LABORATORIES | 2002-11-07 | — | — | US | disclosed |
| US-20020147230-A1 | Aminal Diones as potassium channel openers | ABBOTT LABORATORIES | 2002-10-10 | — | — | US | disclosed |
| US-20020028836-A1 | Potassium channel openers | ABBVIE INC. | 2002-03-07 | — | — | US | disclosed |
| US-4719204-A | ANIMAL FEED | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1988-01-12 | — | — | US | disclosed |
| WO-1985003939-A1 | 1alpha-HYDROXYVITAMIN D2 ANALOGS AND PROCESS FOR PREPARING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036233-A1 | SELF-EMULSIFYING DRUG DELIVERY (SEDDS) FOR OPHTHALMIC DRUG DELIVERY | LSS, SBDS, SPAST | PSIP1 2462/4885ALDH1A1 1834/4885TP53 1785/4885 |
| US-20020028836-A1 | Potassium channel openers | KCNJ2, KCNJ11, KCNJ1 | PSIP1 2916/4885ALDH1A1 704/4885TP53 4315/4885 |
| US-20040122218-A1 | Pyrrolopyridine potassium channel openers | KCNJ2, KCNN1, KCNN2 | PSIP1 2256/4885ALDH1A1 1725/4885TP53 3740/4885 |
| US-20030199578-A1 | Naphthalene amides as potassium channel openers | KCNJ2, KCNN2, KCNJ1 | PSIP1 2667/4885ALDH1A1 1856/4885TP53 2545/4885 |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | RNASEH1, RNASEL, DNASE1 | PSIP1 2843/4885ALDH1A1 802/4885TP53 778/4885 |
| US-20020147230-A1 | Aminal Diones as potassium channel openers | KCNJ2, KCNJ11, KCNH1 | PSIP1 4760/4885ALDH1A1 132/4885TP53 4774/4885 |
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | PSIP1 1185/4885ALDH1A1 3226/4885TP53 57/4885 |
| US-10865213-B2 | Max binders as MYC modulators and uses thereof | MYC, MYCBP, MYCBP2 | PSIP1 1185/4885ALDH1A1 3226/4885TP53 57/4885 |
| US-20210290591-A1 | IMMUNOMODULATING UREA AZALIDES | ARG1, IL2, CD209 | PSIP1 3651/4885ALDH1A1 371/4885TP53 939/4885 |
| US-20020165264-A1 | Aminal diones as potassium channel openers | KCNJ2, KCNJ11, KCNH1 | PSIP1 4760/4885ALDH1A1 132/4885TP53 4774/4885 |
| US-20190144466-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | PSIP1 1185/4885ALDH1A1 3226/4885TP53 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.