Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782994 | 0.92 | SSTR4 (0.41) | AGBL2SSTR4PTGER4SYKIP6K1 | |
| SCHEMBL4530860 | 0.84 | LMNA (0.40) | PTGER4IP6K1ACACB | |
| SCHEMBL167767 | 0.81 | AGBL2 (0.39) | AGBL2SSTR4PTGER4HCAR2HDAC3 | |
| SCHEMBL4940831 | 0.76 | SSTR4 (0.40) | AGBL2SSTR4PTGER4HCAR2IP6K1 | |
| SCHEMBL4530859 | 0.75 | ACACB (0.38) | PTGER4IP6K1ACACB | |
| SCHEMBL4537897 | 0.74 | L3MBTL1 (0.43) | SSTR4KMT2A | |
| SCHEMBL6622645 | 0.74 | GPR17 (0.36) | KMT2A | |
| SCHEMBL4537676 | 0.71 | L3MBTL1 (0.49) | KDM4E | |
| SCHEMBL6452278 | 0.70 | CES2 (0.40) | — | |
| SCHEMBL27962302 | 0.70 | PKM (0.45) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635408-B | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-07-22 | — | — | CN | disclosed |