Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896399 | 0.80 | TSHR (0.42) | HSD17B10LMNAALOX15TSHRSMN1; SMN2 | |
| SCHEMBL27896515 | 0.79 | HSD17B10 (0.50) | HSD17B10LMNAALOX15TSHRSMN1; SMN2 | |
| SCHEMBL28054810 | 0.79 | PIK3CD (0.55) | — | |
| SCHEMBL3891473 | 0.70 | HSD17B10 (0.75) | HSD17B10LMNAALOX15TSHRSMN1; SMN2 | |
| SCHEMBL11378388 | 0.66 | HSD17B10 (0.54) | HSD17B10LMNAALOX15TSHRSMN1; SMN2 | |
| SCHEMBL28799525 | 0.65 | OPRK1 (0.35) | POLB | |
| SCHEMBL27896445 | 0.65 | ATM (0.30) | — | |
| SCHEMBL27888737 | 0.65 | SMN1; SMN2 (0.66) | HSD17B10LMNAALOX15TSHRSMN1; SMN2 | |
| SCHEMBL9001940 | 0.64 | GAA (0.70) | HSD17B10TSHRSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL27879619 | 0.64 | TSHR (0.44) | TSHRSMN1; SMN2GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |