Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879637 | 0.86 | CTSS (0.42) | OPRK1CTSSCTSKPOLB | |
| SCHEMBL27896436 | 0.83 | LOXL2 (0.34) | OPRK1HRH3GLSLOXL2CYP2D6 | |
| SCHEMBL27896420 | 0.80 | NAPRT (0.42) | OPRK1HRH3OPRM1 | |
| SCHEMBL27896388 | 0.72 | KMT2A (0.45) | — | |
| SCHEMBL27879627 | 0.70 | VHL (0.65) | VHLPOLB | |
| SCHEMBL27896445 | 0.69 | ATM (0.30) | SCN9A | |
| SCHEMBL28054810 | 0.69 | PIK3CD (0.55) | VHLCTSK | |
| SCHEMBL13272427 | 0.67 | OPRK1 (0.43) | OPRK1CTSSCTSKPOLB | |
| SCHEMBL28799491 | 0.65 | HSD17B10 (0.45) | POLB | |
| SCHEMBL27896408 | 0.64 | MC4R (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |