Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779280 | 0.82 | MGLL (0.44) | HTR7ALDH1A1MGLLPTPN1MAPT | |
| SCHEMBL11514579 | 0.80 | DDX3X (0.45) | ALDH1A1HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL4940220 | 0.80 | MAPT (0.61) | ALDH1A1HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL8969909 | 0.79 | MAPT (0.59) | ALDH1A1HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL1257436 | 0.79 | MAPT (0.59) | ALDH1A1HDAC1MAPTMAPK1L3MBTL1 | |
| SCHEMBL1607864 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HDAC1HDAC6MAPTLMNA | |
| SCHEMBL11475109 | 0.78 | HTR7 (0.49) | HTR7ALDH1A1HDAC6MGLLMAPT | |
| SCHEMBL10795105 | 0.78 | MEN1 (0.46) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL5004348 | 0.78 | HTR7 (0.52) | HTR7ALDH1A1IKBKBPDK1PDK2 | |
| SCHEMBL1607516 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HDAC1HDAC6MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563536-B | Determination of Lp-PLA2 Activity | 旭化成制药株式会社 | 2022-08-02 | — | — | CN | disclosed |