Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919753 | 0.83 | CFTR (0.33) | F11 | |
| SCHEMBL2916643 | 0.83 | LMNA (0.33) | CRHR1 | |
| SCHEMBL2920369 | 0.83 | PARP15 (0.30) | — | |
| SCHEMBL2921842 | 0.83 | F11 (0.33) | F11 | |
| SCHEMBL2922204 | 0.83 | DDR1 (0.36) | TSHRF11 | |
| SCHEMBL2921125 | 0.82 | CHRM1 (0.32) | SRC | |
| SCHEMBL24656133 | 0.79 | HCAR1 (0.40) | — | |
| SCHEMBL27852584 | 0.79 | FABP4 (0.32) | TSHR | |
| SCHEMBL27941608 | 0.79 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL27952877 | 0.79 | HSD11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664811-B | (1H-1,2,4-triazol-1-yl) aryl compound and preparation method thereof | IHARA CHEMICAL IND CO. (JP) | 2015-09-16 | — | — | CN | disclosed |
| CN-103664811-A | Aryl (1h-1,2,4-triazol-1-yl) compound, and process for production thereof | IHARA CHEMICAL IND CO | 2014-03-26 | — | — | CN | disclosed |