Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367726 | 0.79 | CYP19A1 (0.54) | SMN1; SMN2MEN1TSHRKMT2ACYP11B1 | |
| SCHEMBL28810898 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1TSHRKMT2ACYP11B1 | |
| SCHEMBL30928337 | 0.77 | CYP19A1 (0.55) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL27956577 | 0.73 | AGER (0.42) | MEN1KMT2ACYP11B1CYP11B2FDPS | |
| SCHEMBL27775796 | 0.72 | CYP11B1 (0.43) | CYP11B1CYP11B2AGERCYP19A1CYP1A2 | |
| SCHEMBL27956581 | 0.72 | CYP17A1 (0.54) | MEN1KMT2ACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27956579 | 0.72 | CYP19A1 (0.53) | TSHRCYP11B1CYP11B2CYP19A1KDM4E | |
| SCHEMBL27956540 | 0.72 | CYP19A1 (0.56) | CYP11B1CYP11B2CYP19A1POLB | |
| SCHEMBL27956564 | 0.72 | HMOX1 (0.59) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9368235 | 0.72 | TBXAS1 (0.44) | SMN1; SMN2MEN1TSHRKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724271-A | Substituted imidazole-1-ethylene compound and application thereof | LUWAN BRANCH RUI JIN HOSPITAL SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE | 2014-04-16 | — | — | CN | disclosed |