Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811060 | 0.79 | TSHR (0.46) | MTNR1AMTNR1BALDH1A1NPSR1HTT | |
| SCHEMBL582321 | 0.75 | CA2 (0.54) | CA2POLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8836870 | 0.74 | ABCB1 (0.41) | CA2APEX1POLBLMNAKMT2A | |
| SCHEMBL583113 | 0.71 | CTSD (0.46) | APEX1ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL581422 | 0.71 | MEN1 (0.40) | CA2APEX1POLBMTNR1AMTNR1B | |
| SCHEMBL2578577 | 0.68 | CA2 (0.61) | CA2POLBMTNR1AMTNR1BHTT | |
| SCHEMBL9185713 | 0.68 | CA2 (0.61) | CA2POLBALDH1A1GAAHTT | |
| SCHEMBL10902744 | 0.68 | GAA (0.55) | CA2POLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25143509 | 0.68 | MTNR1A (0.75) | CA2POLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28746195 | 0.68 | ALDH1A1 (0.53) | POLBALDH1A1GAANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104056663-B | The double reaction center ruthenium catalyst of a kind of face chirality and synthesis thereof and application | 上海交通大学 | 2016-12-28 | — | — | CN | disclosed |
| CN-104056663-A | Planar chiral double-reactive center ruthenium catalyst and synthesis and application thereof | UNIV SHANGHAI JIAOTONG | 2014-09-24 | — | — | CN | disclosed |