Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947284 | 0.72 | — | — | |
| SCHEMBL20390137 | 0.72 | BDKRB2 (0.33) | HSD11B1BDKRB2SIGMAR1 | |
| SCHEMBL11568926 | 0.72 | BDKRB2 (0.33) | HSD11B1BDKRB2SIGMAR1 | |
| SCHEMBL19987632 | 0.71 | SIGMAR1 (0.34) | HSD11B1BDKRB2SIGMAR1 | |
| SCHEMBL10858558 | 0.69 | SIGMAR1 (0.32) | HSD11B1SIGMAR1 | |
| SCHEMBL17609571 | 0.67 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL18174976 | 0.66 | — | — | |
| SCHEMBL22231070 | 0.66 | — | — | |
| SCHEMBL10943620 | 0.66 | SIGMAR1 (0.32) | HSD11B1SIGMAR1 | |
| SCHEMBL10721925 | 0.66 | SIGMAR1 (0.33) | HSD11B1BDKRB2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245675-B | Cyclic amides as MetAP-2 inhibitors | 默克专利股份公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-104245675-A | Cyclic amides as MetAP-2 inhibitors | MERCK PATENT GMBH | 2014-12-24 | — | — | CN | disclosed |