Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20390137 | 0.71 | BDKRB2 (0.33) | HSD11B1 | |
| SCHEMBL11568926 | 0.71 | BDKRB2 (0.33) | HSD11B1 | |
| SCHEMBL19987632 | 0.70 | SIGMAR1 (0.34) | HSD11B1 | |
| SCHEMBL29012979 | 0.68 | PRCP (0.31) | — | |
| SCHEMBL31343236 | 0.68 | PRCP (0.31) | — | |
| SCHEMBL29019534 | 0.67 | PRCP (0.30) | — | |
| SCHEMBL28815344 | 0.67 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL10858558 | 0.67 | SIGMAR1 (0.32) | HSD11B1 | |
| SCHEMBL29012929 | 0.66 | — | — | |
| SCHEMBL5492945 | 0.66 | HSD11B1 (0.34) | HSD11B1DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746445-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY (US) | 2020-12-09 | — | — | EP | claimed |
| CN-111655693-A | Inhibition of transient receptor potential A1 ion channels | 伊莱利利公司 | 2020-09-11 | — | — | CN | claimed |
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | claimed |
| WO-2019152465-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY (US) | 2019-08-08 | — | — | WO | claimed |
| US-10221177-B2 | Inhibiting the transient receptor potential A1 ion channel | HYDRA BIOSCIENCES, INC. (US) | 2019-03-05 | — | — | US | claimed |
| US-20170275285-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY | 2017-09-28 | — | — | US | claimed |
| EP-3193880-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | Hydra Biosciences, Inc. (US) | 2017-07-26 | — | — | EP | claimed |
| WO-2016044792-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2016-03-24 | — | — | WO | claimed |
| EP-4233871-A2 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | Eli Lilly and Company (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-111655693-B | Inhibition of transient receptor potential A1 ion channels | 伊莱利利公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11161849-B2 | Inhibiting the transient receptor potential al ion channel | ELI LILLY AND COMPANY (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200392136-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY | 2020-12-17 | — | — | US | disclosed |
| EP-3746445-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY (US) | 2020-12-09 | — | — | EP | disclosed |
| CN-111655693-A | Inhibition of transient receptor potential A1 ion channels | 伊莱利利公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20190330212-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY | 2019-10-31 | — | — | US | disclosed |
| WO-2019152465-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY (US) | 2019-08-08 | — | — | WO | disclosed |
| US-10221177-B2 | Inhibiting the transient receptor potential A1 ion channel | HYDRA BIOSCIENCES, INC. (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170275285-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | ELI LILLY AND COMPANY | 2017-09-28 | — | — | US | disclosed |
| EP-3193880-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | Hydra Biosciences, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044792-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2016-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221177-B2 | Inhibiting the transient receptor potential A1 ion channel | TRPV1, TRPA1, TRPV2 | HSD11B1 1988/4885DPP4 3069/4885DPP7 2440/4885 |
| US-11161849-B2 | Inhibiting the transient receptor potential al ion channel | TRPV1, TRPA1, TRPV2 | HSD11B1 2072/4885DPP4 3175/4885DPP7 2452/4885 |
| US-20200392136-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | TRPV1, TRPA1, TRPV2 | HSD11B1 1988/4885DPP4 3069/4885DPP7 2440/4885 |
| US-20170275285-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | TRPV1, TRPA1, TRPV2 | HSD11B1 1988/4885DPP4 3069/4885DPP7 2440/4885 |
| US-20190330212-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | TRPV1, TRPA1, TRPV2 | HSD11B1 1988/4885DPP4 3069/4885DPP7 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.