Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525176 | 0.85 | NOS2 (0.40) | CTSKNOS2CTSLCTSB | |
| SCHEMBL28858540 | 0.83 | NOS2 (0.36) | NOS2 | |
| SCHEMBL28313701 | 0.81 | NOS2 (0.40) | NOS2 | |
| SCHEMBL28868753 | 0.75 | LDHA (0.41) | NOS2 | |
| SCHEMBL28787513 | 0.74 | ROCK1 (0.37) | NOS2 | |
| SCHEMBL28047241 | 0.74 | NOS2 (0.33) | NOS2 | |
| SCHEMBL28039334 | 0.74 | CTSK (0.32) | CTSKCTSLCTSBPRKCAPRKCD | |
| SCHEMBL27972554 | 0.74 | ROCK2 (0.41) | NOS2 | |
| SCHEMBL28036513 | 0.74 | MEN1 (0.34) | CTSK | |
| SCHEMBL27909167 | 0.74 | CTSK (0.32) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104774205-A | N1/N2-lactam acetyl-coa carboxylase inhibitors | PFIZER | 2015-07-15 | — | — | CN | disclosed |
| CN-103189377-B | N1/n2-lactam acetyl-coa carboxylase inhibitors | PFIZER | 2015-02-25 | — | — | CN | disclosed |