Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844044 | 0.80 | HTR2A (0.39) | BRD4CREBBPP2RX7SIGMAR1TDP2 | |
| SCHEMBL23605538 | 0.79 | KCNK3 (0.52) | KCNK3 | |
| SCHEMBL28818558 | 0.79 | KCNK3 (0.48) | KCNK3BRD4CREBBPP2RX7TRPM2 | |
| SCHEMBL29844211 | 0.74 | CTSS (0.46) | KCNK3BRD4CREBBPP2RX7TRPM2 | |
| SCHEMBL30044769 | 0.70 | SPTLC1 (0.49) | KCNK3BRD4CREBBPP2RX7TRPM2 | |
| Hydrochloric Acid SCHEMBL31163291 | 0.69 | HTR2A (0.46) | TRPM2 | |
| SCHEMBL17290703 | 0.68 | SCN9A (0.44) | SIGMAR1TDP2SCN9AKDM4EALDH1A1 | |
| SCHEMBL29954930 | 0.68 | MEN1 (0.42) | SIGMAR1TDP2SCN9AKDM4EALDH1A1 | |
| SCHEMBL29954402 | 0.68 | SCN9A (0.41) | SIGMAR1TDP2NPC1RAB9ASCN9A | |
| SCHEMBL34469258 | 0.66 | DPP4 (0.40) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |