Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 10/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 10/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 10/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 10/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077906 | 0.70 | ABCC9 (0.52) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL2782039 | 0.64 | ABCC9 (0.50) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL12965356 | 0.60 | PDK1 (0.59) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL14086882 | 0.58 | PDK1 (0.65) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL16212234 | 0.58 | PDK1 (0.70) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL6359557 | 0.58 | PDK1 (1.00) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL28050469 | 0.58 | PDK1 (1.00) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL3129785 | 0.57 | PDK1 (0.67) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL8866461 | 0.57 | ABCC9 (0.69) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL14086867 | 0.57 | PDK1 (0.54) | PDK1PDK2PDK3PDK4ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102711454-B | Methods and compositions for enhancing delivery, expression or activity of RNA interference agents | AU JESSIE L S | 2015-05-20 | — | — | CN | disclosed |