Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 12/20 | 0.52 |
| ▸ | KCNJ11 | Q14654 | 12/20 | 0.52 |
| ▸ | KCNJ8 | Q15842 | 12/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782039 | 0.85 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL6658076 | 0.72 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL3953118 | 0.71 | CYP2C19 (0.52) | KMT2AMEN1CYP3A4CYP2D6TSHR | |
| SCHEMBL8866461 | 0.70 | ABCC9 (0.69) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL28820241 | 0.70 | PDK1 (0.37) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL1289338 | 0.70 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL8866328 | 0.69 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL14086882 | 0.67 | PDK1 (0.65) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL16212234 | 0.67 | PDK1 (0.70) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL776342 | 0.67 | HTR6 (0.44) | KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764511-B | Composition and method for treating cancer | 艾普托斯生物科学公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-105764511-A | Compositions and methods for treating cancers | 艾普托斯生物科学公司 | 2016-07-13 | — | — | CN | disclosed |