Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 5/20 | 0.67 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.67 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.67 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978046 | 0.92 | MAPT (0.66) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL14086882 | 0.85 | PDK1 (0.65) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL83110 | 0.84 | L3MBTL1 (0.78) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL14849461 | 0.84 | PDK1 (0.63) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL5572747 | 0.83 | PDK1 (0.62) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL5572749 | 0.83 | PDK1 (0.62) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL436619 | 0.83 | PDK1 (0.61) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL6789904 | 0.82 | PDK1 (0.60) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL18086475 | 0.81 | L3MBTL1 (0.59) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL5201283 | 0.81 | L3MBTL1 (0.54) | PDK1PDK2PDK3PDK4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914712-B2 | Antibacterial thiazolecarboxylic acids | ANTABIO SAS (FR) | 2018-03-13 | — | — | US | disclosed |
| US-7645898-B2 | Selective androgen receptor modulators and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2010-01-12 | — | — | US | disclosed |
| US-20070173546-A1 | Selective androgen receptor modulators and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2007-07-26 | — | — | US | disclosed |
| US-20070123563-A1 | Selective androgen receptor modulators and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2007-05-31 | — | — | US | disclosed |
| EP-0002892-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173546-A1 | Selective androgen receptor modulators and method of use thereof | AR, SHBG, ESRRA | PDK1 1256/4885PDK2 2857/4885PDK3 1622/4885 |
| US-20070123563-A1 | Selective androgen receptor modulators and method of use thereof | AR, SHBG, ESRRA | PDK1 1256/4885PDK2 2857/4885PDK3 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.