Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.45 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.42 |
| ▸ | OXTR | P30559 | 2/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823981 | 0.88 | DHODH (0.54) | DHODHMAPTPOLBHSD11B1ALDH1A1 | |
| SCHEMBL28824135 | 0.86 | CAMKK2 (0.47) | — | |
| SCHEMBL28949292 | 0.84 | SCN9A (0.47) | DHODH | |
| SCHEMBL28824037 | 0.83 | MCL1 (0.46) | EGLN1HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28823984 | 0.82 | BRS3 (0.43) | SMN1; SMN2 | |
| SCHEMBL28824023 | 0.81 | KDM4C (0.44) | MAPTPOLBHSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28824005 | 0.81 | ALDH1A1 (0.42) | HSD11B1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28824102 | 0.81 | MAPK9 (0.46) | DHODHHSD11B1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28824043 | 0.81 | KMT2A (0.49) | EGLN1MAPTHSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29851972 | 0.79 | TSHR (0.44) | MAPTHSD11B1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |