Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823984 | 0.91 | BRS3 (0.43) | GAANPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824097 | 0.87 | BCAT2 (0.53) | ALOX5APFEN1GRM5CHEK1EIF4E | |
| SCHEMBL28824025 | 0.87 | NPC1 (0.39) | KDM4CTSHRMAPK1HSD11B1MAPT | |
| SCHEMBL28824144 | 0.86 | ALOX5AP (0.43) | ALOX5APFEN1MAPTPOLBALDH1A1 | |
| SCHEMBL28824042 | 0.86 | MEN1 (0.56) | ALOX5APALDH1A1GAASMN1; SMN2F10 | |
| SCHEMBL28824037 | 0.84 | MCL1 (0.46) | TSHRHSD11B1ALDH1A1GAANPC1 | |
| SCHEMBL28824005 | 0.82 | ALDH1A1 (0.42) | MAPK1HSD11B1ALDH1A1GAANPC1 | |
| SCHEMBL28824030 | 0.82 | DHODH (0.48) | HSD11B1MAPTALDH1A1NPC1HSP90AA1 | |
| SCHEMBL28824043 | 0.82 | KMT2A (0.49) | HSD11B1MAPTALDH1A1NPC1HSP90AA1 | |
| SCHEMBL29851972 | 0.80 | TSHR (0.44) | TSHRHSD11B1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |