Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824044 | 0.88 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1NFE2L2 | |
| SCHEMBL28823984 | 0.87 | BRS3 (0.43) | KMT2ASMN1; SMN2GAA | |
| SCHEMBL28824023 | 0.86 | KDM4C (0.44) | SMN1; SMN2ALDH1A1ALOX5APF10GAA | |
| SCHEMBL28824097 | 0.84 | BCAT2 (0.53) | SMN1; SMN2ALDH1A1ALOX5APF10 | |
| SCHEMBL28824144 | 0.83 | ALOX5AP (0.43) | MEN1KMT2AALDH1A1ALOX5APMALT1 | |
| SCHEMBL28824037 | 0.81 | MCL1 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28824005 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1F10 | |
| SCHEMBL28824043 | 0.79 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28824102 | 0.79 | MAPK9 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1F10 | |
| SCHEMBL29851972 | 0.77 | TSHR (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |