Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 3/20 | 0.49 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938676 | 0.85 | MTNR1A (0.42) | DRD2MTNR1AMTNR1BRAB9A | |
| SCHEMBL15938081 | 0.78 | MTNR1A (0.40) | MAPK3MTNR1AMTNR1BMAPT | |
| SCHEMBL28824484 | 0.78 | MET (0.35) | MAPK3 | |
| SCHEMBL28824480 | 0.77 | ALDH1A1 (0.41) | MAPK3 | |
| SCHEMBL6678480 | 0.76 | CA1 (0.50) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8399570 | 0.76 | ACHE (0.46) | MAPK3MTNR1AMTNR1BKDM4ENPC1 | |
| SCHEMBL26162146 | 0.75 | ALDH1A1 (0.44) | SUV39H2DRD2MTNR1AMTNR1BCA12 | |
| SCHEMBL15938784 | 0.75 | SMN1; SMN2 (0.48) | MAPK3 | |
| SCHEMBL28044047 | 0.75 | ALDH1A1 (0.40) | MAPK3MTNR1AMTNR1B | |
| SCHEMBL17102727 | 0.74 | ACHE (0.36) | MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188371-A | Erk inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-23 | — | — | CN | disclosed |