Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043315 | 0.90 | GABBR2 (0.33) | GABRA1GABRB2GABBR2GABBR1 | |
| SCHEMBL1042458 | 0.86 | GABRA1 (0.31) | GABRA1GABRB2GABBR2GABBR1 | |
| SCHEMBL27274680 | 0.81 | SMN1; SMN2 (0.50) | POLBCYP1A2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5699601 | 0.80 | GABRA1 (0.40) | GABRA1GABRB2POLBCYP1A2ALDH1A1 | |
| SCHEMBL2545977 | 0.76 | GABRA1 (0.37) | GABRA1GABRB2POLBCYP1A2ALDH1A1 | |
| SCHEMBL29572569 | 0.73 | CYP1A2 (0.37) | GABRA1GABRB2POLBCYP1A2ALDH1A1 | |
| SCHEMBL1042617 | 0.73 | SMN1; SMN2 (0.42) | POLBCYP1A2ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL25468636 | 0.72 | GABRA1 (0.42) | GABRA1GABRB2POLBCYP1A2ALDH1A1 | |
| SCHEMBL28682542 | 0.71 | GABRA1 (0.33) | GABRA1GABRB2POLBCYP1A2ALDH1A1 | |
| SCHEMBL9347288 | 0.71 | ALDH1A1 (0.39) | CYP1A2ALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | claimed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | claimed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | claimed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | claimed |
| CN-113896875-B | Intramolecular trifunctional Lewis acid-base pair catalyst, annular topological structure PMMBL polymer, preparation method and application | 吉林大学 | 2022-05-31 | — | — | CN | disclosed |
| US-7847126-B2 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2010-12-07 | — | — | US | disclosed |
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | disclosed |
| US-20070299273-A1 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| US-7030200-B2 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20050245702-A1 | Catalysts for olefin polymerization | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2005-11-03 | — | — | US | disclosed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2003076450-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-18 | — | — | WO | disclosed |
| EP-0712828-A1 | Process for preparing an aldehyde | DSM N.V. (NL) | 1996-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245702-A1 | Catalysts for olefin polymerization | PNMT, PPOX, ETFA | GABRA1 4105/4885GABRB2 3632/4885POLB 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.