Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 3/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042021 | 0.89 | GABBR2 (0.36) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL17594503 | 0.87 | POLB (0.44) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7058213 | 0.84 | ALDH1A1 (0.46) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1042661 | 0.84 | GABRA1 (0.34) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4074776 | 0.82 | GABRA1 (0.33) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28928342 | 0.79 | CYP2C19 (0.35) | GABRA1GABRB2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL31519169 | 0.78 | ALDH1A1 (0.56) | POLBALDH1A1SMN1; SMN2ALOX15CYP1A2 | |
| SCHEMBL22861251 | 0.78 | — | — | |
| SCHEMBL28175612 | 0.77 | NR5A2 (0.40) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28803391 | 0.76 | ALOX15 (0.50) | GABRA1GABRB2POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145050-A1 | SULPHONYL UREA DERIVATIVES AS NLRP3 INFLAMMASOME MODULATORS | NodThera Limited (GB) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145050-A1 | SULPHONYL UREA DERIVATIVES AS NLRP3 INFLAMMASOME MODULATORS | NLRP3, NOD1, IL1B | GABRA1 2892/4885GABRB2 3388/4885POLB 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.