Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069748 | 0.85 | CA1 (0.32) | — | |
| SCHEMBL28093777 | 0.84 | SLC6A3 (0.40) | — | |
| SCHEMBL27332909 | 0.82 | HPGDS (0.38) | TSHRRARARARBRARG | |
| SCHEMBL28005777 | 0.81 | DHODH (0.32) | RARARARBRARG | |
| SCHEMBL28099170 | 0.81 | CA1 (0.40) | — | |
| SCHEMBL27330148 | 0.81 | MCL1 (0.40) | RARARARBRARG | |
| SCHEMBL28049312 | 0.79 | RXRA (0.34) | — | |
| SCHEMBL28014013 | 0.75 | MAPK1 (0.35) | TSHRPTGS2 | |
| SCHEMBL28016489 | 0.75 | KMO (0.46) | RARARARBRARGPTGS2 | |
| SCHEMBL28841114 | 0.74 | CES2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593211-A | Indol and indazol derivatives | HOFFMANN LA ROCHE | 2016-05-18 | — | — | CN | disclosed |