Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830809 | 0.87 | DRD4 (0.62) | DRD4KMT2AMEN1GAAMAPT | |
| SCHEMBL28830757 | 0.85 | TSHR (0.60) | DRD4KMT2AMEN1USP2GAA | |
| SCHEMBL27997566 | 0.84 | MEN1 (0.51) | DRD4KMT2AMEN1USP2HTT | |
| SCHEMBL28076624 | 0.83 | HTR1A (0.52) | DRD4KMT2AMEN1GAAADRB2 | |
| SCHEMBL28076582 | 0.79 | CYP2D6 (0.55) | DRD4GAAADRB2ADRB1ADRB3 | |
| SCHEMBL28076704 | 0.78 | GAA (0.56) | DRD4KMT2AMEN1GAAADRB2 | |
| SCHEMBL28076769 | 0.78 | HTR1A (0.52) | MAPT | |
| SCHEMBL28225671 | 0.77 | HTR1A (0.45) | DRD4KMT2AMEN1GAAADRB2 | |
| SCHEMBL28816404 | 0.77 | ABCB1 (0.47) | DRD4KMT2AMEN1USP2HTT | |
| Hydrochloric Acid SCHEMBL11542328 | 0.76 | KMT2A (0.61) | DRD4KMT2AMEN1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |