Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842843 | 0.80 | TDP1 (0.43) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL11561386 | 0.78 | L3MBTL1 (0.51) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL13103938 | 0.76 | ALDH1A1 (0.47) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL25104672 | 0.71 | KMT2A (0.42) | L3MBTL1MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL16639430 | 0.70 | ADORA3 (0.54) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL25813368 | 0.70 | LMNA (0.37) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL30481961 | 0.69 | PTK2 (0.40) | L3MBTL1ALDH1A1PTK2TDP1 | |
| SCHEMBL25323093 | 0.69 | PTK2 (0.40) | L3MBTL1ALDH1A1PTK2TDP1 | |
| SCHEMBL1445865 | 0.68 | ALDH1A1 (0.42) | L3MBTL1MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL15942900 | 0.68 | ALDH1A1 (0.46) | L3MBTL1MAPTALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853752-B | Preparation and application of BTK inhibitor pyrido heterocyclic compound | 药雅科技(上海)有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022166468-A1 | BRUTON'S TYROSINE KINASE INHIBITOR AND APPLICATION THEREOF | 药雅科技(上海)有限公司 | 2022-08-11 | — | — | WO | disclosed |
| CN-114853752-A | Preparation and application of BTK inhibitor pyridine heterocyclic compound | 药雅科技(上海)有限公司 | 2022-08-05 | — | — | CN | disclosed |