Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28831838 | 0.82 | MAOB (0.36) | TDP1PIK3CDPIK3R1MTORALDH1A1 | |
| SCHEMBL29847092 | 0.81 | TDP1 (0.40) | TDP1ALDH1A1LMNAHTTSIRT6 | |
| SCHEMBL4094748 | 0.79 | TDP1 (0.42) | TDP1ALDH1A1LMNAHTTSIRT6 | |
| SCHEMBL21468545 | 0.76 | TDP1 (0.48) | TDP1ALDH1A1LMNASIRT6KMT2A | |
| SCHEMBL18937271 | 0.74 | TERT (0.48) | TDP1ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL16896891 | 0.74 | L3MBTL1 (0.48) | TDP1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL28831852 | 0.72 | SIRT6 (0.47) | TDP1ALDH1A1LMNAHTTSIRT6 | |
| SCHEMBL3022688 | 0.70 | ALDH1A1 (0.57) | TDP1ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL16896874 | 0.69 | MMP12 (0.44) | TDP1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL15797122 | 0.68 | MAPT (0.41) | TDP1ALDH1A1LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115038707-B | Azepine condensed ring compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115038707-A | Azepine condensed ring compound and medical application thereof | 中国医药研究开发中心有限公司 | 2022-09-09 | — | — | CN | disclosed |