Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28900107 | 0.71 | SIRT6 (0.61) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL29400478 | 0.71 | GAA (0.70) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL2926607 | 0.71 | GAA (0.70) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL5627921 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL5054798 | 0.70 | PRKDC (0.55) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL29358 | 0.70 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL1129582 | 0.70 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL4826905 | 0.70 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAHSD17B10HPGD | |
| SCHEMBL12495084 | 0.70 | LMNA (0.59) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL26614109 | 0.69 | HTT (0.62) | ALDH1A1KDM4EGAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| EP-3901138-A1 | COMPOUND FOR USE IN RETINAL DISEASES | Medshine Discovery Inc. (CN) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020125659-A1 | COMPOUND FOR USE IN RETINAL DISEASES | 南京明德新药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ALDH1A2, ALDH1A3, NR2E3 | ALDH1A1 15/4885KDM4E 4093/4885GAA 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.