Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870375 | 0.76 | KMT2A (0.82) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL2439156 | 0.76 | KDM4E (1.00) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL7983695 | 0.75 | PKLR (0.69) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL580862 | 0.73 | KDM4E (0.64) | KDM4EMEN1KMT2AMAPTHPGD | |
| Demethylwedelolactone SCHEMBL3364302 | 0.73 | MEN1 (0.72) | KDM4EMEN1KMT2AMAPTHPGD | |
| Demethylwedelolactone SCHEMBL31146849 | 0.73 | MEN1 (0.72) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL27617272 | 0.72 | HSD17B3 (0.61) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL28057934 | 0.70 | MAOA (0.69) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL31573813 | 0.70 | MAOA (0.69) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL2318335 | 0.70 | MAOA (0.66) | KDM4EMAPTHPGDMCL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989127-A | Compound separated from gentisic acid and separation method and application thereof | 北京先通国际医药科技股份有限公司 | 2022-09-02 | — | — | CN | disclosed |