Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258357 | 0.90 | ADRA2B (0.38) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL258356 | 0.90 | ALDH1A1 (0.37) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL2941939 | 0.78 | CA2 (0.34) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL2941933 | 0.68 | TSHR (0.34) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL12212104 | 0.66 | CA12 (0.35) | CA12CA9CA1CA2CYP1A2 | |
| SCHEMBL11026913 | 0.65 | TDP1 (0.33) | ATMTDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4060227 | 0.64 | — | — | |
| SCHEMBL11044196 | 0.64 | ALDH1A1 (0.38) | ALDH1A1NPSR1MAPTHPGDHSD17B10 | |
| SCHEMBL11149674 | 0.63 | GAA (0.34) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23331403 | 0.62 | ALDH1A1 (0.38) | ALDH1A1NPSR1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010513662-A | — | — | 2010-04-30 | — | — | JP | claimed |
| EP-2125946-A2 | PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME | Dow Global Technologies Inc. (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008088487-A2 | PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2008-07-24 | — | — | WO | claimed |
| EP-2514788-A1 | Phosphorus-sulfur flame retardant additives and polymer systems containing same | Dow Global Technologies LLC (US) | 2012-10-24 | — | — | EP | disclosed |