SCHEMBL2941933

SCHEMBL2941933

CC1(C)COP(=S)(N(Cc2ccccc2)[PH]2(S(=O)(=O)O)OCC(C)(C)CO2)OC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.32
CA2 P00918 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 4/20 0.31
HPGD P15428 3/20 0.31
MAPT P10636 2/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 2/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258356 0.73 ALDH1A1 (0.37) TSHRKDM4ECA2NPSR1ALDH1A1
SCHEMBL2884181 0.68 CA12 (0.33) TSHRKDM4ECA2NPSR1ALDH1A1
SCHEMBL258357 0.62 ADRA2B (0.38) TSHRKDM4ECA2NPSR1ALDH1A1
SCHEMBL12212104 0.60 CA12 (0.35) CA2CYP1A2CYP2C9CYP2C19CA12
SCHEMBL11026913 0.59 TDP1 (0.33) CYP1A2CYP2C9CYP2C19GAA
SCHEMBL23331403 0.59 ALDH1A1 (0.38) NPSR1MEN1KMT2AALDH1A1HPGD
Sulfuric Acid SCHEMBL6574025 0.57 ALDH1A1 (0.74) TSHRKDM4ECA2MEN1KMT2A
Sulfuric Acid SCHEMBL6574021 0.57 ALDH1A1 (0.74) TSHRKDM4ECA2MEN1KMT2A
SCHEMBL4419871 0.56 CA2 (0.54) TSHRKDM4ECA2MEN1KMT2A
SCHEMBL8763535 0.55 ALDH1A1 (0.71) TSHRCA2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010513662-A 2010-04-30 JP claimed
EP-2125946-A2 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME Dow Global Technologies Inc. (US) 2009-12-02 EP claimed
WO-2008088487-A2 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES, INC. (US) 2008-07-24 WO claimed