SCHEMBL258357

SCHEMBL258357

CC1(C)CO[P](S)(N(Cc2ccccc2)[P]2(S)OCC(C)(C)CO2)OC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRK1 P41145 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
G6PC1 P35575 6/20 0.36
AOC3 Q16853 1/20 0.35
NPSR1 Q6W5P4 3/20 0.35
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
OPRM1 P35372 1/20 0.34
OPRL1 P41146 1/20 0.34
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2884181 0.90 CA12 (0.33) ADRA2BADRA2CSLC6A2HTR2ASLC6A4
SCHEMBL258356 0.81 ALDH1A1 (0.37) TSHRALDH1A1G6PC1AOC3NPSR1
SCHEMBL2941939 0.70 CA2 (0.34) TSHRALDH1A1NPSR1CA12CA9
SCHEMBL11149674 0.68 GAA (0.34) ALDH1A1NPSR1
SCHEMBL12212104 0.65 CA12 (0.35) CA12CA9CA2CA1
SCHEMBL4060237 0.65
SCHEMBL11026913 0.64 TDP1 (0.33) ATMTDP1
SCHEMBL14691148 0.63 TSHR (0.43) ADRA2BADRA2CSLC6A2HTR2ASLC6A4
SCHEMBL4060227 0.62
SCHEMBL24359444 0.61 MEN1 (0.33) TSHRALDH1A1NPSR1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2514788-B1 Phosphorus-sulfur flame retardant additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-01 EP disclosed
EP-2514788-A1 Phosphorus-sulfur flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-10-24 EP disclosed
US-8058332-B2 Phosphorus-sulfur FR additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-15 US disclosed
US-20110034573-A1 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME THE DOW CHEMICAL COMPANY 2011-02-10 US disclosed
US-20080153950-A1 Phosphorus-sulfur FR additives and polymer systems containing same DCOMCO, INC. 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153950-A1 Phosphorus-sulfur FR additives and polymer systems containing same TST, FRG1, PFAS ADRA2B 4709/4885ADRA2C 4801/4885SLC6A2 4386/4885
US-20110034573-A1 PHOSPHORUS-SULFUR FR ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME TST, FRG1, PFAS ADRA2B 4709/4885ADRA2C 4801/4885SLC6A2 4386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.