Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846076 | 0.91 | LTA4H (0.52) | LTA4HCNR2SLC5A1IDO1 | |
| SCHEMBL28302613 | 0.87 | L3MBTL1 (0.50) | LTA4HCNR2SLC5A1L3MBTL1TDP1 | |
| SCHEMBL12923849 | 0.85 | LTA4H (0.55) | LTA4HCNR2SAE1UBA2SLC5A1 | |
| SCHEMBL18674031 | 0.85 | LTA4H (0.59) | LTA4HSAE1UBA2IDO1L3MBTL1 | |
| SCHEMBL16339028 | 0.85 | LTA4H (0.59) | LTA4HSAE1UBA2IDO1ATM | |
| SCHEMBL7471697 | 0.84 | MEN1 (0.46) | LTA4HCNR2SLC5A1IDO1L3MBTL1 | |
| SCHEMBL1539299 | 0.84 | ACHE (0.48) | LTA4HCNR2L3MBTL1MAPT | |
| SCHEMBL27557356 | 0.83 | LTA4H (0.49) | LTA4HTDP1NPC1LMNARAB9A | |
| SCHEMBL16383178 | 0.82 | ACHE (0.52) | LTA4HCNR2SAE1UBA2L3MBTL1 | |
| SCHEMBL23116737 | 0.81 | CA2 (0.57) | LTA4HSAE1UBA2IDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106604727-A | Compositions and methods to improve adoptive cell therapies | 7山利益有限责任公司 | 2017-04-26 | — | — | CN | disclosed |