Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539299 | 0.93 | ACHE (0.48) | LTA4HCNR2 | |
| SCHEMBL27557356 | 0.92 | LTA4H (0.49) | LTA4H | |
| SCHEMBL28842002 | 0.91 | LTA4H (0.55) | LTA4HCNR2IDO1SLC5A1 | |
| SCHEMBL15719428 | 0.90 | CYP19A1 (0.49) | LTA4H | |
| SCHEMBL11292183 | 0.89 | LTA4H (0.58) | LTA4HCYP11B1CYP11B2 | |
| SCHEMBL28302613 | 0.89 | L3MBTL1 (0.50) | LTA4HCNR2SLC5A1 | |
| SCHEMBL11295684 | 0.88 | GPR84 (0.47) | CNR2 | |
| SCHEMBL25005866 | 0.87 | PABPC1 (0.44) | — | |
| SCHEMBL7471697 | 0.86 | MEN1 (0.46) | LTA4HCNR2IDO1SLC5A1 | |
| SCHEMBL17141665 | 0.83 | KCNJ1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |