SCHEMBL9513083

SCHEMBL9513083

COC(=O)c1ccccc1CS(=O)(=O)C#N

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
TSHR P16473 1/20 0.45
HIF1A Q16665 1/20 0.44
CFTR P13569 1/20 0.44
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GLA P06280 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15461583 0.81 ALDH1A1 (0.57) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL7363401 0.81 ALDH1A1 (0.57) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL4880583 0.80 CA1 (0.58) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL2884550 0.80 ALDH1A1 (0.55) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL2427784 0.78 ALDH1A1 (0.57) ALDH1A1LMNAKDM4EHSD17B10TSHR
SCHEMBL29548152 0.78 ALDH1A1 (0.57) ALDH1A1LMNAKDM4EHSD17B10TSHR
SCHEMBL4912518 0.77 ALDH1A1 (0.53) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL646787 0.77 L3MBTL1 (0.54) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL9657864 0.77 ALDH1A1 (0.49) ALDH1A1LMNAKDM4EHSD17B10CA1
SCHEMBL29539868 0.77 ALDH1A1 (0.49) ALDH1A1LMNAKDM4EHSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563208-A1 SULPHONYL FORMAMIDOXIMES, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE AGAINST PLANT PESTS Hoechst Schering AgrEvo GmbH (DE) 1993-10-06 EP disclosed
WO-1992011237-A1 SULPHONYL FORMAMIDOXIMES, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE AGAINST PLANT PESTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-09 WO disclosed