Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5949996 | 0.97 | TDP1 (0.40) | SIRT2ALDH1A1LMNATDP1MAPT | |
| SCHEMBL29219009 | 0.84 | SNCA (0.43) | SIRT2ALDH1A1LMNATDP1MAPT | |
| SCHEMBL27888371 | 0.78 | ESPL1 (0.43) | SIRT2ALDH1A1LMNATDP1MAPT | |
| SCHEMBL9229136 | 0.70 | CTSB (0.34) | SIRT2ALDH1A1LMNAMAPTCASP6 | |
| SCHEMBL30123443 | 0.69 | SNCA (0.49) | SIRT2ALDH1A1LMNATDP1MAPT | |
| SCHEMBL3600632 | 0.69 | LMNA (0.56) | SIRT2ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL6653019 | 0.67 | ROCK1 (0.54) | SIRT2ALDH1A1LMNATDP1MAPT | |
| SCHEMBL28845915 | 0.67 | ALDH1A1 (0.37) | SIRT2ALDH1A1TDP1MAPTMCL1 | |
| SCHEMBL2123168 | 0.66 | NOTUM (0.57) | ALDH1A1LMNAMAPTRAB9APOLB | |
| SCHEMBL14976087 | 0.65 | RORC (0.50) | ALDH1A1LMNAMAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073934-A | Benzisothiazole heterocyclic azo dye and preparation method thereof | 青岛理工大学 | 2022-09-20 | — | — | CN | claimed |
| CN-115725189-A | Bisazo disperse dye and synthetic method and application thereof | 绍兴文理学院 | 2023-03-03 | — | — | CN | disclosed |
| CN-115386244-A | Double-chromophore pH color-changing reactive dye and preparation and application thereof | 南通大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-115073934-A | Benzisothiazole heterocyclic azo dye and preparation method thereof | 青岛理工大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073934-A | Benzisothiazole heterocyclic azo dye and preparation method thereof | 青岛理工大学 | 2022-09-20 | — | — | CN | disclosed |