Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28171062 | 0.96 | EPHX1 (0.49) | ALDH1A1MAPTSMN1; SMN2DRD2CAMK2A | |
| SCHEMBL28171778 | 0.94 | EPHX1 (0.51) | ALDH1A1MAPTSMN1; SMN2CAMK2AEPHX1 | |
| Bicarbonate SCHEMBL6207408 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2DRD2CA1 | |
| SCHEMBL28171748 | 0.79 | AKR1C3 (0.47) | ALDH1A1CA1CA2EPHX1KDM1A | |
| SCHEMBL28164088 | 0.78 | PPARG (0.46) | ALDH1A1MAPTSMN1; SMN2EPHX1HSD11B1 | |
| SCHEMBL1515026 | 0.78 | DRD2 (0.59) | ALDH1A1MAPTSMN1; SMN2DRD2CA1 | |
| SCHEMBL17731492 | 0.76 | DGAT1 (0.52) | ALDH1A1MAPTSMN1; SMN2DRD2 | |
| SCHEMBL28849545 | 0.75 | EPHX1 (0.56) | ALDH1A1SMN1; SMN2KMT2AEPHX1TSHR | |
| SCHEMBL9408365 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2DRD2CA1 | |
| SCHEMBL9408374 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2DRD2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205970-A | Immunomodulator | 弗莱塞斯生物科学公司 | 2017-09-26 | — | — | CN | disclosed |