Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254705 | 0.82 | KEAP1 (0.63) | ALOX5LTA4HCALM1KEAP1SLC5A2 | |
| SCHEMBL2579095 | 0.81 | ALOX5 (0.54) | ALOX5LTA4HCALM1SLC5A1MEN1 | |
| SCHEMBL12869627 | 0.78 | LTA4H (0.60) | LTA4HSLC5A2SLC5A1MEN1KMT2A | |
| SCHEMBL2577502 | 0.78 | LTA4H (0.50) | ALOX5LTA4HCALM1MEN1KMT2A | |
| SCHEMBL11511612 | 0.77 | HSPA5 (0.54) | KEAP1MEN1KMT2A | |
| SCHEMBL28842004 | 0.77 | LTA4H (0.53) | ALOX5LTA4HSLC5A2SLC5A1 | |
| SCHEMBL2580758 | 0.76 | ALOX5 (0.49) | ALOX5LTA4HCALM1MEN1KMT2A | |
| SCHEMBL4289115 | 0.76 | ALDH1A1 (0.51) | ALOX5LTA4HMEN1KMT2AVKORC1 | |
| SCHEMBL2576280 | 0.76 | CALM1 (0.54) | ALOX5LTA4HCALM1 | |
| SCHEMBL28251912 | 0.75 | LTA4H (0.72) | LTA4HMEN1KMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |