Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 5/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SGK1 | O00141 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31691426 | 0.81 | ALOX15 (0.47) | PKMPOLBKDM4EMAPTNPC1 | |
| SCHEMBL31691389 | 0.80 | KMT2A (0.47) | SYKAURKBINCENPPKMPOLB | |
| SCHEMBL2987181 | 0.80 | PARP10 (0.50) | EGFRSYKAURKBINCENPPOLB | |
| SCHEMBL7834117 | 0.79 | PKM (0.60) | PKMPOLBKDM4EMAPTNPC1 | |
| SCHEMBL4664597 | 0.77 | EGFR (0.60) | EGFRSLC2A1PTGS2SGK1CAMKK2 | |
| SCHEMBL19512975 | 0.75 | SLC6A3 (0.52) | KDM4EMAPTLMNAALOX15HTT | |
| SCHEMBL28787158 | 0.74 | EGFR (0.52) | EGFRSLC2A1PTGS2MAPTMEN1 | |
| SCHEMBL27621631 | 0.74 | EGFR (0.56) | EGFRSLC2A1PTGS2SGK1CAMKK2 | |
| SCHEMBL19474955 | 0.73 | ALDH1A1 (0.56) | PKMPOLBKDM4ELMNAALOX15 | |
| SCHEMBL7443031 | 0.73 | DHFR (0.44) | SYKPKMKDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124677-B | Meltable metallic organic framework material and covalent organic framework material, and preparation methods and uses thereof | 首都师范大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-115124677-A | Meltable metal organic framework material and covalent organic framework material, preparation method and application thereof | 首都师范大学 | 2022-09-30 | — | — | CN | disclosed |