Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898230 | 1.00 | LMNA (0.40) | LMNAPOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28857652 | 0.84 | MAPT (0.48) | LMNAPOLBRAB9AMAPTHTT | |
| SCHEMBL28857617 | 0.83 | ESR1 (0.43) | LMNAPOLBRAB9ANPC1MAPT | |
| SCHEMBL28857603 | 0.81 | MEN1 (0.45) | LMNAPOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28857616 | 0.80 | POLB (0.49) | LMNAPOLBRAB9ASMN1; SMN2TP53 | |
| SCHEMBL29898258 | 0.80 | POLB (0.49) | LMNAPOLBRAB9ASMN1; SMN2TP53 | |
| SCHEMBL28857607 | 0.79 | SMN1; SMN2 (0.46) | LMNAPOLBSMN1; SMN2HTTKDM4E | |
| SCHEMBL29898221 | 0.79 | SMN1; SMN2 (0.46) | LMNAPOLBSMN1; SMN2HTTKDM4E | |
| SCHEMBL28857620 | 0.79 | TNIK (0.49) | LMNAPOLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28857574 | 0.78 | MGLL (0.48) | LMNAPOLBRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |