Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898230 | 0.84 | LMNA (0.40) | MAPTKDM4ERAB9ALMNAPOLB | |
| SCHEMBL28857602 | 0.84 | LMNA (0.40) | MAPTKDM4ERAB9ALMNAPOLB | |
| SCHEMBL28857617 | 0.84 | ESR1 (0.43) | MAPTRAB9ALMNAPOLBHTT | |
| SCHEMBL29898258 | 0.83 | POLB (0.49) | MAPTALDH1A1RAB9ALMNAPOLB | |
| SCHEMBL28857616 | 0.83 | POLB (0.49) | MAPTALDH1A1RAB9ALMNAPOLB | |
| SCHEMBL29898221 | 0.82 | SMN1; SMN2 (0.46) | KDM4ELMNAPOLBMEN1KMT2A | |
| SCHEMBL28857620 | 0.82 | TNIK (0.49) | MAPTKDM4EALDH1A1RAB9ALMNA | |
| SCHEMBL28857607 | 0.82 | SMN1; SMN2 (0.46) | KDM4ELMNAPOLBMEN1KMT2A | |
| SCHEMBL28857574 | 0.81 | MGLL (0.48) | MAPTRAB9ALMNAPOLBHTT | |
| SCHEMBL28857590 | 0.81 | POLB (0.51) | MAPTKDM4EALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |