Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18661304 | 0.86 | MAPK1 (0.41) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL1768308 | 0.84 | MAPK1 (0.39) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL28693643 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL13319607 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL4611987 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL598477 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL22717278 | 0.70 | LMNA (0.40) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL7714896 | 0.68 | LMNA (0.39) | ALDH1A1MAPK1ESR1ESR2MAPT | |
| SCHEMBL7929465 | 0.68 | CRHBP (0.42) | ALDH1A1MAPK1MAPTLMNAHTT | |
| SCHEMBL18904960 | 0.68 | LMNA (0.48) | ALDH1A1MAPK1ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164391-A | A kind of biphenyl compound and its application in 1,3- dibromo pyrenes are prepared | 李现伟 | 2018-06-15 | — | — | CN | disclosed |