Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256682 | 0.81 | MEN1 (0.33) | SMN1; SMN2MEN1KMT2ATP53MAPT | |
| SCHEMBL27826908 | 0.80 | MAOA (0.33) | KMT2AMAPTALDH1A1HTT | |
| SCHEMBL19212451 | 0.80 | GPR119 (0.47) | SMN1; SMN2USP2LMNATP53HPGD | |
| SCHEMBL29707311 | 0.80 | GPR119 (0.47) | SMN1; SMN2USP2LMNATP53HPGD | |
| SCHEMBL28293019 | 0.78 | LMNA (0.36) | SMN1; SMN2LMNATP53MAPTALDH1A1 | |
| SCHEMBL27621448 | 0.74 | MAPT (0.38) | KDM4ESMN1; SMN2LMNATP53HPGD | |
| SCHEMBL19212237 | 0.74 | SMN1; SMN2 (0.38) | KDM4ESMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL28808789 | 0.72 | HDAC3 (0.32) | SMN1; SMN2KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL27697694 | 0.70 | MEN1 (0.40) | KDM4ESMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL27869396 | 0.70 | MEN1 (0.31) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |