Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23866983 | 0.82 | LOXL2 (0.51) | MGLLCYP4A11MMP2MMP3LOXL2 | |
| SCHEMBL7614719 | 0.80 | CYP4A11 (0.50) | MGLLCYP4A11LOXL2CYP4F2GRM2 | |
| SCHEMBL27903348 | 0.79 | HDAC8 (0.43) | — | |
| SCHEMBL4951937 | 0.77 | CTSS (0.40) | CA2 | |
| SCHEMBL25336125 | 0.77 | CYP4A11 (0.44) | MGLLCYP4A11LOXL2CYP4F2GRM2 | |
| SCHEMBL9657880 | 0.76 | CYP4A11 (0.41) | CYP4A11MMP2MMP3LOXL2CYP4F2 | |
| SCHEMBL28063313 | 0.76 | CYP4A11 (0.51) | MGLLCYP4A11LOXL2CYP4F2GRM2 | |
| SCHEMBL28261558 | 0.75 | MGLL (0.46) | MGLLCYP4A11LOXL2CYP4F2GRM2 | |
| SCHEMBL6286529 | 0.74 | CYP4A11 (0.42) | CYP4A11MMP2MMP3LOXL2CYP4F2 | |
| SCHEMBL23912343 | 0.74 | CYP4A11 (0.60) | CYP4A11LOXL2CYP4F2MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884058-A | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | 阿奇克斯制药公司 | 2018-11-23 | — | — | CN | disclosed |