Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948574 | 0.88 | POLB (0.42) | LMNATSHRMAPK1HTTGRM2 | |
| SCHEMBL23536112 | 0.88 | POLB (0.42) | LMNATSHRMAPK1HTTGRM2 | |
| SCHEMBL29931915 | 0.87 | ALDH1A1 (0.39) | LMNAHTTGRM2DRD2ADRA1D | |
| SCHEMBL29931877 | 0.84 | CA2 (0.43) | GRM2DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL23536117 | 0.83 | POLB (0.41) | LMNAHTTGRM2TP53POLB | |
| SCHEMBL29931921 | 0.83 | POLB (0.41) | LMNAHTTGRM2TP53POLB | |
| SCHEMBL23536108 | 0.81 | PGR (0.43) | LMNADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL29931982 | 0.81 | PGR (0.43) | LMNADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL29931965 | 0.81 | GRM2 (0.41) | GRM2DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL29931984 | 0.76 | CYP1A2 (0.39) | HTTGRM2DRD2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |