Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27328296 | 0.98 | BLM (0.46) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL27468299 | 0.91 | TSHR (0.55) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL2227903 | 0.85 | LMNA (0.48) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL2825360 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL27951470 | 0.83 | BLM (0.46) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL28000197 | 0.82 | KMT2A (0.35) | LMNAKMT2ATHRBCYP1A2BLM | |
| Adipic Acid SCHEMBL11074254 | 0.81 | LMNA (0.65) | LMNASLC22A6TSHRHDAC11KMT2A | |
| Adipic Acid SCHEMBL11077556 | 0.81 | LMNA (0.65) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL9003618 | 0.81 | ARG1 (0.57) | LMNASLC22A6TSHRHDAC11KMT2A | |
| SCHEMBL1300781 | 0.81 | ARG1 (0.57) | LMNASLC22A6TSHRHDAC11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12527880-B2 | Cyanine-based telodendrimers and uses for treating cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-01-20 | — | — | US | claimed |
| US-20250000811-A1 | TELODENDRIMER NANOCARRIERS FOR MONOMERIC AMPHOTERICIN B DELIVERY | UNIV NEW YORK STATE RES FOUND (US) | 2025-01-02 | — | — | US | claimed |
| US-11649326-B2 | Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-05-16 | — | — | US | claimed |
| US-20230076792-A1 | SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-03-09 | — | — | US | claimed |
| CN-115551917-A | Sequential targeting of cross-linked nanotherapeutics for the treatment of brain tumors | 加利福尼亚大学董事会 | 2022-12-30 | — | — | CN | claimed |
| US-11406714-B2 | Telodendrimers and nanocarriers and methods of using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-08-09 | — | — | US | claimed |
| EP-3347053-B1 | FUNCTIONAL, SEGREGATED, CHARGED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR STATE UNIV OF NEW YORK (US) | 2022-05-25 | — | — | EP | claimed |
| US-11219692-B2 | Porphyrin modified telodendrimers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-11 | — | — | US | claimed |
| US-20210346518-A1 | CYANINE-BASED TELODENDRIMERS AND USES FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-11 | — | — | US | claimed |
| CN-113330056-A | Cyanine-based terminal dendritic copolymers and their use for the treatment of cancer | 加利福尼亚大学董事会 | 2021-08-31 | — | — | CN | claimed |
| US-20160038605-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-02-11 | — | — | US | claimed |
| EP-2931290-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | The Regents of The University of California (US) | 2015-10-21 | — | — | EP | claimed |
| WO-2015027054-A2 | TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-02-26 | — | — | WO | claimed |
| US-20150056139-A1 | TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-26 | — | — | US | claimed |
| WO-2014093675-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-19 | — | — | WO | claimed |
| US-20140161719-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-12 | — | — | US | claimed |
| EP-2707419-A2 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | The Regents of the University of California (US) | 2014-03-19 | — | — | EP | claimed |
| WO-2012158622-A2 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-22 | — | — | WO | claimed |
| EP-2344134-A2 | NANOCARRIERS FOR DRUG DELIVERY | The Regents of the University of California (US) | 2011-07-20 | — | — | EP | claimed |
| WO-2010039496-A2 | NANOCARRIERS FOR DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346518-A1 | CYANINE-BASED TELODENDRIMERS AND USES FOR TREATING CANCER | TYR, LGALS3, ABL1 | LMNA 2523/4885SLC22A6 2253/4885TSHR 1907/4885 |
| US-20140161719-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | CETP, NR1H4, ABCB4 | LMNA 2451/4885SLC22A6 379/4885TSHR 647/4885 |
| US-12527880-B2 | Cyanine-based telodendrimers and uses for treating cancer | TUBB1, CA13, YWHAZ | LMNA 4046/4885SLC22A6 856/4885TSHR 1069/4885 |
| US-20230076792-A1 | SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS | TIE1, CA12, CA13 | LMNA 3488/4885SLC22A6 969/4885TSHR 2376/4885 |
| US-11406714-B2 | Telodendrimers and nanocarriers and methods of using same | TTI2, MTCL3, HTT | LMNA 1494/4885SLC22A6 2701/4885TSHR 669/4885 |
| US-20150056139-A1 | TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME | TTI2, MTCL3, HTT | LMNA 1494/4885SLC22A6 2701/4885TSHR 669/4885 |
| US-20160038605-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | CETP, NR1H4, ABCB4 | LMNA 2451/4885SLC22A6 379/4885TSHR 647/4885 |
| US-11649326-B2 | Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same | TSPO, TBCA, TTI2 | LMNA 3051/4885SLC22A6 748/4885TSHR 917/4885 |
| US-11219692-B2 | Porphyrin modified telodendrimers | CETP, NR1H4, ABCB4 | LMNA 2451/4885SLC22A6 379/4885TSHR 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.