SCHEMBL28868424

SCHEMBL28868424

CCCCCCCCNc1cc(-c2ccc(-c3ccccc3)cc2)cc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.47
CYP1A2 P05177 2/20 0.47
SOAT1 P35610 4/20 0.43
SOAT2 O75908 2/20 0.41
KIF11 P52732 1/20 0.41
TRIM58 Q8NG06 1/20 0.40
KCNH3 Q9ULD8 1/20 0.40
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
STAT1 P42224 1/20 0.39
RAB9A P51151 1/20 0.39
ABL1 P00519 1/20 0.39
NPY1R P25929 1/20 0.39
NPY5R Q15761 1/20 0.39
CNR2 P34972 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28868452 0.94 TRPA1 (0.49) TRPA1CYP1A2KIF11ALDH1A1NPY1R
SCHEMBL28643723 0.82 SOAT1 (0.54) SOAT1SOAT2TRIM58KCNH3ALDH1A1
SCHEMBL6231339 0.81 TRPA1 (0.46) TRPA1CYP1A2MAPTABL1CNR2
SCHEMBL5647753 0.81 KIF11 (0.55) KIF11ABL1
SCHEMBL7089257 0.79 ALDH1A1 (0.52) SOAT1SOAT2TRIM58KCNH3ALDH1A1
SCHEMBL27669287 0.79 ALDH1A1 (0.52) SOAT1SOAT2TRIM58KCNH3ALDH1A1
SCHEMBL25590656 0.77 LMNA (0.54) ALDH1A1MAPTABL1NPY1RNPY5R
SCHEMBL5647265 0.76 KIF11 (0.56) KIF11
SCHEMBL7574473 0.76 RIPK1 (0.49) TRPA1CYP1A2MAPTCNR2
SCHEMBL6235877 0.75 LMNA (0.55) ALDH1A1MAPTABL1NPY1RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232019-B Synthesis method of 3-acetamido benzotrifluoride compound 闽江学院 2023-10-27 CN disclosed
CN-115232019-A Synthetic method of 3-acetamido benzotrifluoride compound 闽江学院 2022-10-25 CN disclosed