Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | IAPP | P10997 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637954 | 1.00 | GLA (0.60) | GLATDP1CYP3A4PTPN1PTGS1 | |
| SCHEMBL29931049 | 1.00 | GLA (0.60) | GLATDP1CYP3A4PTPN1PTGS1 | |
| SCHEMBL2887149 | 1.00 | GLA (0.60) | GLATDP1CYP3A4PTPN1PTGS1 | |
| SCHEMBL14016920 | 0.92 | IAPP (0.66) | GLATDP1CYP3A4PTPN1PTGS1 | |
| SCHEMBL2744147 | 0.85 | CYP3A4 (0.61) | CYP3A4PTPN1PTGS1CYP1A2MEN1 | |
| SCHEMBL2744149 | 0.85 | CYP3A4 (0.61) | CYP3A4PTPN1PTGS1CYP1A2MEN1 | |
| SCHEMBL9579426 | 0.84 | PTGS1 (0.61) | GLATDP1CYP3A4PTGS1IAPP | |
| SCHEMBL78427 | 0.83 | RELA (0.62) | GLATDP1CYP3A4PTPN1PTGS1 | |
| SCHEMBL78426 | 0.83 | RELA (0.62) | GLATDP1CYP3A4PTPN1PTGS1 | |
| SCHEMBL6552210 | 0.83 | RELA (0.62) | GLATDP1CYP3A4PTPN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502109-A1 | TRIAZOLE-PHENYL-THIAZOLE HETEROCYCLES AS INNOVATIVE INHIBITORS OF TRYPANOTHIONE REDUCTASE AND THEIR USE AS LEISHMANICIDES | Consejo Superior De Investigaciones Científicas (ES) | 2019-06-26 | — | — | EP | disclosed |
| US-8309715-B2 | Camphor-derived β-amino alcohol compounds, method for manufacturing the same and asymmetric addition of organozinc to aldehydes using the same | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-11-13 | — | — | US | disclosed |
| US-20110313159-A1 | CAMPHOR-DERIVED BETA-AMINO ALCOHOL COMPOUNDS, METHOD FOR MANUFACTURING THE SAME AND ASYMMETRIC ADDITION OF ORGANOZINC TO ALDEHYDES USING THE SAME | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-22 | — | — | US | disclosed |
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | MSD K.K. (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2042478-A1 | METHOD FOR PRODUCING -DIARYL ELECTRON-WITHDRAWING GROUP SUBSTITUTED COMPOUND | Japan Science and Technology Agency (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-4680400-A | Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-07-14 | — | — | US | disclosed |
| US-4640708-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313159-A1 | CAMPHOR-DERIVED BETA-AMINO ALCOHOL COMPOUNDS, METHOD FOR MANUFACTURING THE SAME AND ASYMMETRIC ADDITION OF ORGANOZINC TO ALDEHYDES USING THE SAME | ADH1C, DDC, DCXR | GLA 3862/4885TDP1 4369/4885CYP3A4 1480/4885 |
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | BMP6, GPR6, ACSL6 | GLA 1172/4885TDP1 3153/4885CYP3A4 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.